Table 3. Inhibition of MDMA-induced 5-HT or NE release by different inhibitors.

	SERT		NET
	EC50 (µM) (95% CI)	Emax, % retained, (95% CI)	EC50 (µM) (95% CI)	Emax, % retained, (95% CI)
MDMA alone	1.69 (1.07–2.66)	48 (42–55)	0.55 (0.17–1.81)	78 (73–82)
MDMA plus 0.1 µM duloxetine	3.51 (0.46–27)	82 (75–90)	0.59 (0.02–19)	90 (84–97)
MDMA plus 0.1 µM citalopram	3.17 (1.89–5.31)	72 (68–77)	na	na
MDMA plus 0.1 µM reboxetine	na	Na	3.35 (0.63–179)	78 (56–102)
MDA alone	2.77 (1.78–4.30)	48 (41–54)	0.85 (0.29–2.55)	73 (67–79)
MDA plus 0.1 µM duloxetine	6.86 (0.5–100)	83 (77–89)	2.06 (0.35–12.12)	80 (73–87)
MDA plus 0.1 µM citalopram	5.0 (1.28–19.6)	59 (44–75)	na	na

95% CI, 95% confidence interval; na, not assessed.