Table 2. Expression of synovial phenotypic and vascular markers in patients who fulfilled 2010 ACR/EULAR criteria for RA at baseline after follow up and in the patients who fulfilled1987 ACR criteria.
| RA 2010 (n = 23) | RA 1987 (n = 33) | P-value | |
| CD3 (count/mm2) | 201(856) | 198(795) | 0.86 |
| CD55 (count/mm2) | 1,144 (1,253) | 1,163 (1,365) | 0.89 |
| CD68L (count/mm2) | 274(275) | 234 (396) | 0.84 |
| CD68SL (count/mm2) | 571 (1,054) | 393 (1562) | 0.92 |
| CD22 (count/mm2) | 170 (470) | 214 (330) | 0.94 |
| CD138 (count/mm2) | 53 (504) | 139 (564) | 0.98 |
| Tryptase (count/mm2) | 235 (445) | 338(345) | 0.13 |
| vWF (IOD/mm2) | 205,845 (175,450) | 171,078 (167,211) | 0.75 |
| VEGF (IOD/mm2) | 59,435 (157,527) | 63,461 (81,425) | 0.86 |
| VCAM-1 (IOD/mm2) | 119,676 (298,344) | 184,267 (265,919) | 0.70 |
Values are presented as median (interquartile range). A Mann-Whitney U test was used to compare the different diagnostic groups; a P-value of <0.05 was considered statistically significant. RA = rheumatoid arthritis. CD3 refers to T cells; CD55– fibroblast-like synoviocytes; CD68– macrophages; CD22– B cells; CD138– plasma cells; tryptase – mast cells. L = intimal lining layer; SL = synovial sublining; vWF = von Willebrand factor; VEGF = vascular endothelial growth factor; VCAM-1 = vascular cell adhesion molecule-1. IOD = integrated optical density.