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STIM1 is required for NFAT-driven gene expression in response to LTC4. (A) Knockdown of STIM1 reduces NFAT-dependent GFP expression after stimulation with 120 nM LTC4 for 40 min. Control denotes stimulation with LTC4 in mock-transfected cells. (B) Knockdown of STIM2 does not impair gene expression to LTC4. (C) Aggregate data from several experiments is compared.
