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. Author manuscript; available in PMC: 2013 May 15.
Published in final edited form as: J Immunol. 2012 Apr 18;188(10):5073–5085. doi: 10.4049/jimmunol.1102143

FIGURE 3. Malaria infected TLR9−/− and MyD88−/− mice differentially produce cytokines.

FIGURE 3

WT, TLR2−/−, TLR4−/−, TLR9−/− and MyD88−/− mice (n = 5 in each group) were infected with P. yoelii. Blood from the infected mice at 5, 10, and 17 days postinfection was collected, and sera prepared. TNF-α (A), IFN-γ (B), IL-12 (C), IL-10 (D) and IL-4 (E) present in the pooled sera were measured by ELISA. Experiments were performed two times and each time ELISA was performed in duplicates. The letters, a, b and c, represent the statistical significance between the levels of cytokines produced by the indicated gene knockout mice and those produced by the corresponding infected WT mice. a, p <0.001; b, p <0.01; c, p <0.05.