Table 1. Hif modulates immune responses in renal macrophages.

CD11b⁺ cells were isolated from UUO kidneys 8 days after ureteral ligation using the MACS beads system. For each experimental set, CD11b⁺ cells were pooled from 3 to 5 littermates (mutant and control mice each). qRT-PCR analysis was performed with pooled CD11b⁺ cells and gene expression was normalized to 18S rRNA. Alterations in gene expression are presented as fold-changes over pooled littermate controls.

Gene	LysM-Hif−/−		LysM-Vhl−/−
	Set 1	Set 2	Set 1	Set2
iNos	2.13	3.22	0.75	0.72
Arginase I	0.65	0.81	0.65	0.81
Mr	0.53	1.66	0.80	0.51
Tnfa	0.62	0.89	0.77	0.55
Il-10	0.63	1.00	0.89	0.29
Ccr 2	2.03	1.83	0.76	0.81
Ccr 5	2.99	2.53	0.72	0.71