Table 1.
Demographic Data | Controls | MJ Smokers | 1-way ANOVA Significance |
---|---|---|---|
N | 28(19M, 9F) | 34(29M, 5F) | - |
Handedness | 26R, 2L | 31R, 3L | - |
Age | 24.32±6.65 | 22.76±6.57 | NS |
WASI (four-factor) | |||
VIQ | 122.00±11.45 | 119.69±14.43 | NS |
PIQ | 118.93±15.08 | 118.66±14.52 | NS |
MJ-Related Variables | |||
Urinary THC/creatinine level (ng/ml) | - | 414.13±556.11 | - |
Age of Onset | - | 15.53±2.16 | - |
Smokes/Week | - | 19.24±19.58 | - |
Grams/Week | - | 10.86±14.95 | - |
Duration of Use (yrs) | - | 7.24±7.30 | - |
Clinical Data | |||
BDI | 2.19±2.86 | 1.91±3.22 | NS |
PANAS | |||
Positive | 32.59±5.79 | 32.26±5.58 | NS |
Negative | 11.37±2.12 | 12.62±3.46 | NS |
POMS | |||
Vigor | 20.56±3.95 | 19.33±4.40 | NS |
Anger | 3.12±3.91 | 4.70±4.33 | NS |
Confusion | 4.77±3.94 | 5.18±2.59 | NS |
Tension | 5.79±5.17 | 5.48±3.67 | NS |
Fatigue | 4.21±3.40 | 4.12±2.64 | NS |
Depression | 3.75±3.87 | 3.21±4.00 | NS |
Total Mood Disturbance | 1.08±17.72 | 3.36±15.04 | NS |
HAM-A | 1.81±2.48 | 2.12±2.16 | NS |
BIS | |||
Attention | 15.32±3.85 | 16.93±2.36 | 0.062 |
Motor | 19.60±4.89 | 22.57±4.04 | 0.017 |
Non-Planning | 24.28±4.73 | 26.77±5.15 | 0.070 |
Total | 59.20±10.28 | 66.27±8.80 | 0.008 |
Neurocognitive Data | |||
WCST | |||
Deck 1 Categories | 4.45±1.14 | 3.87±1.34 | NS |
Deck 2 Categories | 4.64±0.58 | 4.23±1.02 | 0.096 |
Total Categories | 9.09±1.38 | 8.19±2.10 | 0.086 |
Deck 1 Perseverations | 3.41±2.84 | 7.61±6.98 | 0.010 |
Deck 2 Perseverations | 2.27±2.21 | 3.42±3.66 | NS |
Total Perseverations | 5.68±3.55 | 11.03±9.28 | 0.013 |
Loss of Set Deck 1 | 0.09±0.29 | 0.19±0.40 | NS |
Loss of Set Deck 2 | 0.09±0.29 | 0.39±0.50 | 0.015 |
Total Losses of Set | 0.18±0.40 | 0.58±0.72 | 0.022 |
Stroop Color Word Test | |||
Color Naming % Accuracy | 93.89±6.04 | 93.89±6.53 | NS |
Color Naming Commissions | 2.00±2.42 | 2.24±2.24 | NS |
Word Reading % Accuracy | 99.08±1.81 | 98.01±3.11 | NS |
Word Reading Commissions | 0.29±0.54 | 1.45±1.99 | 0.004 |
Interference % Accuracy | 96.63±5.61 | 92.96±11.41 | NS |
Interference Commissions | 1.46±2.87 | 2.64±3.64 | NS |
Trail Making Test | |||
A Time (sec) | 21.25±5.96 | 22.50±5.69 | NS |
A Errors | 0.11±0.32 | 0.25±0.51 | NS |
B Time (sec) | 42.61±14.37 | 49.66±14.51 | 0.064 |
B Errors | 0.21±0.50 | 0.28±0.46 | NS |
ROCF | |||
Copy Raw Score | 32.02±3.60 | 31.32±3.92 | NS |
Delayed Recall Raw Score | 21.46±6.86 | 20.84±5.79 | NS |
Digit Span | |||
Forward | 9.89±2.06 | 10.50±4.22 | NS |
Backward | 9.00±2.49 | 8.78±4.14 | NS |
Total | 18.89±3.97 | 18.25±4.11 | NS |
CVLT | |||
Trial 1 Correct | 7.88±1.56 | 7.35±2.12 | NS |
Trials 1–5 Correct | 57.81±8.71 | 55.35±8.96 | NS |
Long Delay Correct | 12.69±2.75 | 12.57±2.97 | NS |
COWAT | |||
Corrected Total | 50.16±9.87 | 48.00±16.13 | NS |
Animals | 25.84±5.90 | 23.00±4.50 | NS |
VIQ = Verbal IQ, PIQ = Performance IQ, THC = Tetrahydrocannabinol, HAM-A = Hamilton Anxiety Rating Scale, BDI = Beck Depression Inventory, PANAS = Positive and Negative Affect Scale, BIS = Barratt Impulsiveness Scale, POMS = Profile of Mood States, WCST = Wisconsin Card Sorting Test, ROCF = Rey-Osterrieth Complex Figure, CVLT = California Verbal Learning Test, COWAT = Controlled Oral Word Association Test