Table 4.

Time course of biochemical paramters in cardiac transplant recipients on low-dose EVL (LD) or high-dose EVL (RD).

Parameter	T 0	T 6	T 12	P value
	LD n = 51; RD n = 56	LD n = 44; RD n = 41	LD n = 39; RD n = 36
Creatinine (mg/dL)
LD group	2.23 ± 0.75	2.06 ± 0.87	2.05 ± 0.79	0.030
RD group	2.06 ± 0.44	2.07 ± 0.83	2.08 ± 0.84	0.725
BUN (mg/dL)
LD group	99 ± 38	81 ± 34	78 ± 29	0.003
RD group	93 ± 37	97 ± 51	90 ± 41	0.420
Triglycerides (mg/dL)
LD group	162 ± 80	198 ± 106	209 ± 116	0.006
RD group	182 ± 107	254 ± 211	253 ± 222	0.063
Total cholesterol (mg/dL)
LD group	206 ± 54	216 ± 62	222 ± 51	0.029
RD group	199 ± 50	228 ± 63	229 ± 56	0.013
HDL-cholesterol (mg/dL)
LD group	57.4 ± 15.7	57.0 ± 19.0	56.0 ± 16.6	0.639
RD group	52.0 ± 15.7	59.4 ± 17.7	59.8 ± 15.4	<0.001
LDL-cholesterol (mg/dL)
LD group	121 ± 45	125 ± 44	123 ± 41	0.815
RD group	119 ± 33	129 ± 42	124 ± 43	0.611
White blood cells (106/L)
LD group	7.58 ± 3.40	6.60 ± 1.89	6.36 ± 2.04	0.202
RD group	7.23 ± 1.77	7.20 ± 1.57	7.11 ± 1.78	0.268
Red blood cells (1012/L)
LD group	4.11 ± 0.61	4.32 ± 0.64	4.48 ± 0.74	<0.001
RD group	4.15 ± 0.59	4.35 ± 0.69	4.44 ± 0.73	0.076
Platelets (109/L)
LD group	218 ± 66	219 ± 65	220 ± 73	0.819
RD group	223 ± 77	224 ± 59	220 ± 52	0.467