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. Author manuscript; available in PMC: 2012 May 6.
Published in final edited form as: J Comp Neurol. 2010 Aug 15;518(16):3290–3301. doi: 10.1002/cne.22400

Figure 6.

Figure 6

In the absence of BDNF, taste buds are significantly smaller in size. Mean taste bud volumes for taste buds located in the tongue were plotted for wild-type, Bdnf−/−, Ntf4/5−/−, and Bdnf−/−/Ntf4/5−/− mice. Deletion of BDNF resulted in a drastic reduction in taste bud volume as compared to wild-type volumes. However, in the absence of NT-4, the surviving taste buds retained their normal size. Bdnf−/−/Ntf4/5−/− mice had very small taste buds, which were even smaller than those in BDNF mutant mice, indicating that in the absence of BDNF, the presence or absence of NT-4 does influence taste bud size. *P < 0.05 versus wild-type.