Figure 8. TNF-α mRNA stability is not induced after UVB irradiation and IL-1α stimulation.
Keratinocytes were UVB or sham-irradiated and stimulated with IL-1α for 3 h. Actinomycin D (10 μg/ml) was added after 3h. Total RNA was extracted at different time points and TNF-α mRNA levels were determined by northern analysis and Real-time PCR. The half-life was calculated in UVB, and UVB+ IL-1α treated cells.