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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Hepatology. 2012 Jan 30;55(6):1662–1672. doi: 10.1002/hep.25533

Fig. 1.

Fig. 1

NS5A domain I directly binds HSP70. The upper part of all panels displays Western analysis of GST pull-down targets (antibodies are mentioned underneath). Arrows indicate presence of target polypeptides. The lower part(s) represent(s) Coomassie stains showing GST-fusion bait proteins. (A) and (B) NS5A directly binds HSP70. (C) Deletion of NS5A domain I abolishes its HSP70 interaction. (D) The membrane anchoring domain of NS5A is not required for HSP70 binding. (E) Only NS5A domain I binds HSP70.