Fig. 2.

Phylogenic relationships among ATXR3 and known histone methyltransferases. An ML tree was drawn using the SET domain sequences of known histone methyltransferases from Arabidopsis and Drosophila, bacterial SET proteins (Polynucleobacter necessarius-1, 2) and proteins that share similar amino acid sequences with ATXR3 (other proteins shown as Organism name-number) with PhyML (Guindon and Gascuel 2003, Guindon et al. 2010). KYP and G9a belong to the SUV39 HOMOLOG (SUVH) H3K9 methyltransferase family, and E(z) and CLF are in the H3K27 methyltransferase family. Numbers next to branches indicate bootstrap statistical support values for branches (1,000 replicates). Bootstrap values >50% are presented. The scale is the estimated branch length indicating the number of substitutions per site.