Table 1.

Some pathogens with steadily increasing prevalence of acquired antibiotic resistance

Pathogens	Drugs	Country	Ref
Vobrio cholerae	cotrimexoxazole, nalidixic	Guinea - Bissau (1987 – 95)	4
	acid, ampicillin	India (1993 – 1995)	4
	ampicillin kana mycin, streptomycin, sulphonamids, tetracycline	Simalia (1985 – 86)	19
Shigella flexneri	ampicillin, tetracycline, sulphonamides, (alone or with trimethoprim)	Bangladesh (1993 –1990)	4
S. dysenteriae	nalidixic acid	Brazil (1983 – 93)	4
		Rwanda (1983 – 1993)	4
		Thailand (1981 – 1995)	15
	ampicillin, cotrimexoxazole, nalidixic acid, mecillinam	Begladesh (1995 – 96)	19
Streptococcus pneumoniae	penicillin, chloramphenicol, cephalosporins	Spain, Mexico, South Africa South Korea,Portugal, Croatia France, USA, Belgium	19
	penecillin	Malawi (1995 – 1997)	18, 22
Neisseria menigitidis	penecillin, chloramphenicol	Sub-saharan Africa
		Malawi (11986 – 1992)	19
		Spain (1985 – 1996)
		UK (1995)	14
		Belgium (1998)
N. gononhoea	penecillins, tetracycline, sulphonamides fluoroquinolones	Phillipines,Thailand, USA	14
S. pyogenes	macrolides, erythromycin	Australia, japan, Finland, Uk Italy, Spain	14
Salmonella typhi	ampicillin, chloramphenicol, cotrimexoxazole	Bangladesh (1989 – 1993)	13, 20
Salmonella (non-typhoidal)	cotrimexoxazole	Thailand (1981 – 1995)	15
		UK (1991 – 1994
		USA
	ampicillin, contrimexoxazole gentamycin	Malawi (1996 – 1998)	21, 22
Enterotoxigenic E.coli	cotrimexoxazole fluoroquinolones	Thailand (1987 – 1995) Spain	15
Campylobacter sp.	fluoroquinolones	Thailand (1987 – 1995 Nehterlands	15
Yersinia pestis	streptomycin, chloramphenicol, tetracycline, gentamycin, spectinomycin, kanamycin, sulphonamides	Madagascar	19
Staphylococcus aureus	methicillin, penecillin	Kenya, Sri Lanka, Tunisia, Severa other Countries	19
Mycobacterium tuberculosis	isoniazid, streptomycin, rifampicin.	over 100 countries	11