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. 2011 Mar 28;33(7):881–888. doi: 10.1093/eurheartj/ehr075

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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2011. For permissions please email: journals.permissions@oup.com.

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(A) Meta-analysis studies genotyped in this paper for association between rs7025486 and coronary heart disease. Combined odds ratio (95% confidence interval) is 1.16 (1.05–1.29); P= 0.003. Fixed-effects additive genotype model. (B) Meta-analysis of association between rs7025486 and coronary heart disease, including newly genotyped, previously published data and genome-wide association study data from the WTCCC and CVHS. Odds ratio 1.10 (95% confidence interval 1.06–1.14, P = 3.2 × 10⁻⁶). Fixed-effects additive genotype model.