FIG 5 .

Effect of deletion of nnrS on colonization of wild-type and iNOS^−/− mutant mice. As described in the legend to Fig. 4, mice were inoculated with a mixture of wild-type (WT) V. cholerae and a ΔnnrS (A) or a ΔhmpA ΔnnrS (B) mutant. In the experiment shown in panel C, mice were inoculated with a mixture of the V. cholerae ΔhmpA and ΔhmpA ΔnnrS mutants and the competitive index is reported as the ratio of ΔhmpA ΔnnrS to ΔhmpA mutant colonies normalized to the input. Error bars indicate 95% confidence intervals. *, P < 0.05; ***, P < 0.001.