Table- I.
Microbe | Classification | Antibiotic of choice (†) | Remarks |
1. Vibrio vulnificus | G-ve bacillus | ceftriaxone+ doxycycline | Causes progressive fasciitis |
2. Citrobacter spp. (C. farmery/C. diversus) |
G-ve coliform | macrolides, floroquinolones, carbapenems |
Produce B-lactamase |
3. Burkholderia pseudomallei |
G-ve aerobic, motile bacillus. | ceftazidime & doxycycline | |
4. Pantoea agglomerans | G-ve aerobic bacillus | ceftriaxone, gentamycin, amikacin, meropenem |
|
5. Bacteroides melaninogenicus |
G-ve, anaerobic motile bacillius | clindamycin, metronidazole, chloramphenicol |
Non-spore forming anaerobe |
6. Aeromonas hydrophila | G-ve bacillus facultative anaerobe |
Pyridine carboxylic acids, chloramphenicol |
Fatal myonecrosis in immunocopromised |
7. Serratia fonticola | G-ve, aerobic | Often multi-resistant | Emerged as human pathogen in 1991 |
8. Clostridium perfringens |
G+ve, anaerobic, spore-forming bacillus. |
Penicillin G, clindamycin, chloramphenicole | |
9. Pseudomonas areogenosa |
G-ve bacillus | 3rd gen. cephalosporins, aminoglycosides, fluoroquinolones |
|
10. Proteus vulgaris | Aerobic, G-ve bacillus. | ceftriaxone, imipenem |
for empirical treatment; microbiological diagnosis should be attempted to further guide antibiotic choice
G-ve, gram negative; G+ve, gram positive