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. 2012 Feb 29;32(5):771–779. doi: 10.1038/jcbfm.2012.15

Figure 2.

Figure 2

(A) Time course of cerebral pH (Inline graphic) during the 3-nitropropionic acid (3NP) intoxication protocol showing a significant increase at day 3 (D3), followed by a significant decrease on day 5 (D5). pH changes appear correlated with succinate dehydrogenase (SDH) inhibition (Inline graphic); (B) magnetic resonance imaging (MRI) images acquired in one rat during the intoxication protocol, demonstrating the absence of MRI-visible lesion before D5 and major striatal lesions at D5.