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Neutrophil depletion with ANS prevents the reductions in mitochondrial membrane potential (top) and respiratory activity (bottom) induced by I/R relative to sham (nonischemic) controls. Data represents means ± SE for 6 rats per group. *P < 0.01 compared with sham group, #P < 0.05 compared with ANS+I/R group. JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide; MTT-FZ, formazan derivative of 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide.
