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Systemic treatment of rats with cortisol and corticosterone inhibited cholangiocyte proliferation after BDL. Rats underwent BDL or sham surgery and were treated with cortisol and corticosterone (1 mg·kg−1·day−1) for 7 days postsurgery. A and B: CK-19-positive cholangiocytes and PCNA-expressing cholangiocytes in liver sections. Values are means ± SE; n = 7. *P < 0.05 vs. sham. #P < 0.05 vs. BDL.
