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. 2012 Mar 8;287(19):15174–15192. doi: 10.1074/jbc.M111.308023

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Effects of hydroxyurea and trimidox on decidua and deciduoma. A, a representative photo showing the weight of implantation site was significantly decreased after pregnant mice were treated with hydroxyurea. B, the quantification of the weight of implantation sites after pregnant mice were treated with hydroxyurea. C, a representative photograph showing mouse uteri on day 7 after day 4 pregnant mice were treated with DMSO (control) or trimidox twice (1800 and 2200 h). D, the weight of implantation site was significantly decreased by trimidox treatment compared with control. E, a representative photo showing the weight of deciduoma was significantly reduced after pseudopregnant mice under artificial decidualization were treated with hydroxyurea. F, the quantification of deciduoma after pseudopregnant mice under artificial decidualization were treated with hydroxyurea. G, relative expression level of Dtprp mRNA in mouse uterus after pseudopregnant mice under artificial decidualization were treated with hydroxyurea. Con, control uterus; Dec, deciduoma; Dec + HU, deciduoma after HU injection. *, p < 0.05; error bars, S.E.