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Steroid hormonal regulation on RRM1 and RRM2 expression. A, real-time RT-PCR of Rrm1 mRNA level after stromal cells were treated with steroid hormones. B, real-time RT-PCR of Rrm2 mRNA level after ovariectomized mice were treated with steroid hormones. C, real-time RT-PCR of Rrm2 mRNA level after stromal cells were treated with steroid hormones. D, the relative luciferase activity of Rrm2 promoter when stromal cells were treated with steroid hormones. *, p < 0.05; error bars, S.E.
