Skip to main content
. 2012 Mar 8;287(19):15174–15192. doi: 10.1074/jbc.M111.308023

FIGURE 6.

FIGURE 6.

Progesterone regulation on RRM2 expression in vivo and in vitro. A, real-time RT-PCR of Rrm2 expression after ovariectomized mice were treated with progesterone for different times. B, Western blot of RRM2 protein after ovariectomized mice were treated with progesterone for different times. C, protein expression of RRM2 in uteri of ovariectomized mice injected with oil, P4, or P4 plus RU486. D, real-time RT-PCR of Rrm2 expression after stromal cells were treated with progesterone for different times. E, real-time RT-PCR of Rrm2 expression after stromal cells were treated with RU486, progesterone, or both progesterone and RU486. F, Northern blot analysis of both transcripts of Rrm2 in stromal cells treated with RU486, progesterone, or both progesterone and RU486. G, Western blot analysis of RRM1 and RRM2 proteins in stromal cells treated with RU486, progesterone, or both progesterone and RU486. *, p < 0.05; error bars, S.E.