Table 2.
Parameter | Placebo n = 18 | Pasireotide | All treatments N = 72 |
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---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||
1 μg n = 6 |
2.5 μg n = 6 |
10 μg n = 6 |
30 μg n = 6 |
100 μg n = 8 |
200 μg n = 4 |
300 μg n = 6 |
600 μg n = 6 |
1200 μg n = 6 |
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Mean age, years (range) | 30.4 (20–40) | 27.5 (19–35) | 29.2 (22–40) | 33.8 (27–39) | 31.8 (21–40) | 28.3 (20–40) | 26.3 (23–34) | 33.3 (24–39) | 31.5 (25–39) | 30.0 (20–40) | 30.3 (19–40) |
Mean height, cm (range) | 180.4 (169–196) | 182.0 (179–185) | 175.0 (166–182) | 177.5 (167 –188) | 182.3 (172–194) | 182.4 (170–193) | 183.5 (170–190) | 178.3 (172–184) | 175.8 (170–183) | 179.8 (169–194) | 179.8 (166–196) |
Mean weight, kg (range) | 76.5 (60.2–86.6) | 76.6 (70.5–81.0) | 68.3 (59.3–80.0) | 72.2 (65.5–79.1) | 75.2 (64.4–88.4) | 74.5 (67.0–83.2) | 81.8 (66.7–93.9) | 73.3 (60.2–79.7) | 73.1 (63.1–78.9) | 74.0 (65.5–82.0) | 74.7 (59.3–93.9) |
Mean elbow breadth, cm (range) | 7.2 (6.3–7.7) | 7.4 (7.2–7.5) | 7.1 (6.7–7.5) | 7.2 (6.8–7.4) | 7.3 (6.9–7.8) | 7.3 (6.9–7.8) | 7.4 (7.0–7.9) | 7.3 (6.9–7.6) | 7.0 (6.5–7.8) | 7.2 (6.9–7.6) | 7.2 (6.3–7.9) |
Race, n (%) | |||||||||||
Caucasian | 16 (88.9) | 6 (100) | 6 (100) | 5 (83.3) | 6 (100) | 8 (100) | 4 (100) | 6 (100) | 6 (100) | 6 (100) | 69 (95.8) |
Black | 1 (5.6) | – | – | 1 (16.7) | – | – | – | – | – | – | 2 (2.8) |
Asian | 1 (5.6) | – | – | – | – | – | – | – | – | – | 1 (1.4) |
Body frame, n (%) | |||||||||||
Small | 4 (22.2) | – | 1 (16.7) | – | 1 (16.7) | 1 (12.5) | – | – | 2 (33.3) | 1 (16.7) | 10 (13.9) |
Medium | 13 (72.2) | 6 (100) | 5 (83.3) | 6 (100) | 5 (83.3) | 7 (87.5) | 3 (75) | 6 (100) | 4 (66.7) | 5 (83.3) | 60 (83.3) |
Large | 1 (5.6) | – | – | – | – | – | 1 (25) | – | – | – | 2 (2.8) |