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Summary of linear regression values between log-parameters and log-dose (doses of pasireotide 2.5–1200 μg)
| PK parameters | Slope | Confidence interval | |
|---|---|---|---|
|
|
|||
| Lower 90% | Upper 90% | ||
| AUC∞ (ng · h/mL) | 1.01 | 0.93 | 1.08 |
| AUClast (ng · h/mL) | 1.14 | 1.09 | 1.19 |
| Cmax (ng · h/mL) | 0.96 | 0.93 | 1.00 |
Abbreviations: AUC, area under the concentration–time curve; Cmax, maximum observed plasma concentration after drug administration.
