Table 2.

Mean breakup area and OPI 2.0 calculations for the entire, central, inferior, and superior cornea for dry eye and normal worst eyes based on staining, forced-stare tear film breakup time, and mean breakup area

	Staining			Forced-stare TFBUT			MBA
	Dry eye	Normal	P value	Dry eye	Normal	P value	Dry eye	Normal	P value
MBA (all)	0.227	0.055	0.003	0.210	0.042	0.001	0.300	0.065	<0.001
MBA (central)	0.035	0.021	0.425	0.034	0.022	0.471	0.053	0.023	0.206
MBA (inferior)	0.152	0.019	0.005	0.155	0.005	<0.001	0.190	0.022	<0.001
MBA (superior)	0.040	0.014	0.217	0.021	0.016	0.691	0.057	0.021	0.104
OPI 2.0 (all)	0.039	0.008	0.003	0.040	0.007	0.002	0.049	0.010	<0.001
OPI 2.0 (central)	0.006	0.004	0.534	0.006	0.004	0.590	0.009	0.004	0.307
OPI 2.0 (inferior)	0.029	0.002	<0.001	0.031	0.001	<0.001	0.034	0.003	<0.001
OPI 2.0 (superior)	0.004	0.002	0.399	0.002	0.003	0.947	0.006	0.003	0.245

Abbreviations: MBA, mean breakup area; OPI 2.0, mean breakup area/interblink interval; TFBUT, tear film breakup time.