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The influence of HR changes on negative inotropic effects of K201. The % change in contractility and relaxation indices (A) and volume indices (B) in paced and unpaced working hearts following 4 min of perfusion with 1.0 µmol·L−1 K201. *P < 0.05, significant effect of K201. §P= 0.05, significant effect of K201. **P < 0.05, significant effect of pacing.
