Figure 8.

The effect of 1 µmol·L⁻¹ K201 on [Ca²⁺]_i and diastolic cell length in isolated rabbit cardiomyocytes under conditions of elevated Ca²⁺ loading. (A, B) Typical traces of [Ca²⁺]_i under conditions indicated above each (red line denotes stimulus mark). (C) Mean ± SEM values for stimulated Ca²⁺ transient (i) peak, (ii) diastolic and (iii) amplitude. (D) Mean ± SEM values for diastolic event (i) frequency and (ii) amplitude. (E) Mean ± SEM values for diastolic cell length (L/L₀). DMSO group (n= 8) and K201 group (n= 6); *P < 0.05, significant differences between groups as shown.