. Author manuscript; available in PMC: 2012 May 7.

Published in final edited form as: Skeletal Radiol. 2011 Apr 9;40(10):1315–1327. doi: 10.1007/s00256-011-1156-9

Table 3.

Distribution of cartilage lesions in terms of their specific semi-quantitative whole-organ magnetic resonance imaging score (WORMS) and quantitative lesion sizes in the subject groups

Compartment	Month	Semiquantitative score (WORMS)				Quantitative score (size)

		Patients	Controls	p values		Patients	Controls	p values

				Slope^a	BL^b			Slope^a	BL^b
Patella
Lateral	BL	4 (0; 6)	1 (0; 4.2)		0.004	66 (0; 408)	6.5 (0; 156.9)		0.009
	12	4 (0; 6)	1 (0; 4.2)	0.003		80 (0; 420)	8 (0; 169.2)	0.010
	24	4 (0; 6)	1 (0; 5.1)			80 (0; 420)	8.5 (0; 180)
Medial	BL	2.5 (0; 6)	0 (0; 4.1)			64 (0; 396)	0 (0; 121.5)		0.014
	12	2.5 (0; 6)	0 (0; 4.1)	0.533		42 (0; 396)	0 (0; 117.3)	0.051
	24	2 (0; 6)	0 (0; 4.1)			51 (0; 396)	0 (0; 126.9)
Femur
Lateral	BL	0 (0; 5)	0 (0; 0)		0.011	0 (0; 189)	0 (0; 0)		0.008
	12	0 (0; 5)	0 (0; 0)	0.919		0 (0; 189)	0 (0; 0)	0.054
	24	0 (0; 5)	0 (0; 0)			0 (0; 189)	0 (0; 0)
Trochlea	BL	2 (0; 5)	0 (0; 3.2)		0.008	45 (0; 357)	0 (0; 60.3)		0.001
	12	2.5 (0; 5)	0 (0; 3.2)	0.066		40 (0; 384)	0 (0; 63.9)	0.002
	24	3 (0; 5)	0 (0; 3.2)			88 (0; 408)	0 (0; 65.1)
Medial	BL	3 (0; 5)	0 (0; 0)		<0.0001	10 (0; 345)	0 (0; 0)		<0.0001
	12	3 (0; 5)	0 (0; 0)	0.120		38 (0; 338)	0 (0; 0)	0.008
	24	3 (0; 5)	0 (0; 0)			36 (0; 360)	0 (0; 0)
Tibia
Lateral	BL	1 (0; 3)	0 (0; 1)		0.002	12 (0; 144)	0 (0; 72.6)		0.006
	12	1 (0; 4)	0 (0; 1)	0.132		14 (0; 120)	0 (0; 74.4)	0.053
	24	1 (0; 4)	0 (0; 1)			15 (0; 135)	0 (0; 58.2)
Medial	BL	0 (0; 5)	0 (0; 0)		<0.0001	0 (0; 96)	0 (0; 0)		0.001
	12	0 (0; 5)	0 (0; 0)	0.551		0 (0; 90)	0 (0; 0)	0.022
	24	0 (0; 5)	0 (0; 0)			0 (0; 90)	0 (0; 0)
Whole knee	BL	14 (6.5; 21)	2 (0; 10.2)		<0.0001	353 (146; 1,339)	54.5 (0; 253.8)		<0.0001
	12	14 (8; 21)	2 (0; 10.2)	0.082		356 (157; 1,384)	55.5 (0; 249.6)	0.026
	24	14 (9; 21)	2 (0; 10.2)			397 (176; 1,402)	76 (0; 278.7)

Results are median values and the 10th and 90th percentiles

p values in bold indicate significant group differences

Intergroup comparison of the slope was performed with generalized estimation equations (GEE) after adjustment for age and BMI

Intergroup comparison of the absolute values at baseline (BL) was conducted with Mann–Whitney U tests