Figure 1.

Qa-1-restricted Vβ8-specific CD8⁺ T cell hybridoma 21–5A9 differentially recognizes TH1 Vβ8⁺CD4⁺ T cells but not TH2 Vβ8⁺CD4⁺ T cells. The CD8⁺ T cell hybridoma was cultured with each of the MBP-specific CD4⁺ clones for 18 h and then assayed for the induction of β-galactosidase activity as described in Materials and Methods. Each data point represents the means of triplicate values minus background.