Table 1.
Group | Treatment |
---|---|
I | PBS |
II | pVAX I |
III | pIRESneo |
IV | pVAX/IL-18 |
V | pVAX/TgPLP1 |
VI | pVAX/MIC6 |
VII | pIRESneo/MIC6/TgPLP1 |
VIII | pIRESneo/MIC6/TgPLP1+pVAX/IL-18 |
Each group consisted of 25 mice. All treatments were injected into the thigh muscle and were given in 100 μl of PBS. For groups II through VIII, 100 μg of plasmid DNA was given. Two weeks after the final inoculation, five mice in each group were challenged intragastrically with 80 cysts of T. gondii strain PRU, and eight mice in each group were orally infected with 20 cysts of strain PRU.