Table 2.
Splenocyte proliferation responses of mice immunized with various plasmidsa
| Group | Proliferation SIb |
|---|---|
| pIRESneo/MIC6/PLP1+pVAX/IL-18 | 8.63 ± 0.15 A |
| pIRESneo/MIC6/PLP1 | 6.74 ± 0.14 B |
| pVAX/PLP1 | 4.20 ± 0.27 C |
| pVAX/MIC6 | 4.29 ± 0.18 C |
| pVAX/IL-18 | 4.18 ± 0.20 C |
| pIRESneo | 0.86 ± 0.03 D |
| pVAX I | 0.90 ± 0.07 D |
| PBS | 0.95 ± 0.11 D |
a
Splenocytes from three mice were harvested 2 weeks after the last immunization.
b
SI, stimulation index. Data followed by different capital letters are significantly different from each other (P < 0.05).