Table 1.
Lytic activity of CS74L, CS74L1-177, and CSCD on sensitive species
| Bacterium | Lytic activitya |
Φ8074-B1 plaque formationb | |||
|---|---|---|---|---|---|
| CS74L | CS74L1-177 | CSCD | CTP1L | ||
| C. sporogenes ATCC 17886 | 59.9 ± 0.3 | 67.8 ± 0.3 | 69.4 +/-1.3 | − | C |
| C. sporogenes NCIMB 10696 | 84.0 ± 0.3 | 61.6 ± 3.4 | 71.2 ± 0.1 | − | R |
| C. sporogenes NCIMB 532 | 53.6 ± 3.7 | 62.8 ± 0.1 | 67.9 ± 0.4 | − | R |
| C. sporogenes NCIMB 9381 | 77.7 ± 1.8 | 21.5 ± 6.4 | 9.6 ± 3.4 | − | R |
| C. sporogenes NCIMB 9382 | 73.3 ± 4.5 | 33.4 ± 5.1 | 58.0 ± 2.2 | − | C |
| C. sporogenes NCIMB 9383 | 78.9 ± 0.5 | 44.3 ± 2.0 | 75.7 ± 1.1 | − | C |
| C. sporogenes NCIMB 12148 | 40.2 ± 0.7 | 68.1 ± 0.2 | 55.8 ± 0.3 | − | R |
| C. sporogenes NCIMB 12343 | 75.9 ± 5.6 | 70.4 ± 1.6 | 80.2 ± 1.1 | − | T |
| C. sporogenes NCIMB 700933 | 54.9 ± 2.0 | 74.8 ± 0.2 | 74.6 ± 1.9 | − | R |
| C. sporogenes NCIMB 701789 | 35.9 ± 0.3 | 72.2 ± 0.8 | 58.6 ± 3.2 | − | c |
| C. sporogenes NCIMB 701791 | 50.7 ± 4.8 | 75.9 ± 2.5 | 66.9 ± 2.1 | − | R |
| C. sporogenes NCIMB 701792 | 65.9 ± 4.7 | 76.3 ± 1.7 | 68.9 ± 1.2 | − | c |
| C. sporogenes NCIMB 701793 | 58.2 ± 1.9 | 73.6 ± 0.2 | 71.9 ± 0.7 | − | R |
| C. sporogenes NCIMB 8053 | 83.4 ± 0.9 | 52.7 ± 2.5 | 74.9 ± 0.9 | − | R |
| C. sporogenes NCDO 1792 | 51.0 ± 0.5 | 67.5 ± 1.2 | 69.0 ± 0.7 | − | c |
| C. sporogenes PA 3679 | 44.7 ± 0.4 | 68.5 ± 1.8 | 64.5 ± 1.4 | − | c |
| C. acetobutylicum BL75141 | 32.5 ± 0.7 | 31.1 ± 1.1 | 48.5 ± 6.0 | − | R |
| C. tyrobutyricum NCIMB 9582 | 52.7 ± 2.5 | 46.5 ± 7.0 | 16.8 ± 4.2 | 57.6 ± 0.6 | R |
a
Percent drop in OD at 600 nm in 8 min (mean ± SD), measured over linear lysis of frozen cells incubated with 10 μg partially purified protein. −, not measured.
b
C, large clear plaques; c, small clear plaques; T, large turbid plaques; R, no plaque formation.