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. 2001 May 15;98(11):6307–6312. doi: 10.1073/pnas.111158698

Figure 4.

Figure 4

Introduction of a TCR transgene does not rescue the tFADD−/− phenotype. (a) Thymic cellularity of 2C T cell receptor transgenic mice (2C) between tFADD−/− and their littermate controls. The scatter plots depict the total thymus cellularity. Column 1 represents the 2C/tFADD−/− mice, and column 2 represents the age-matched littermate control (the genotypes of these mice are either 2C/Tg-FADD/FADD+/−/lck-Cre, 2C/Tg-FADD/FADD+/+, 2C/FADD+/−/lck-Cre, or Tg-FADD/FADD+/−/lck-Cre). Each symbol represents the corresponding littermate. (b) A representative flow cytometric analysis from the thymus of a 2C TCR tFADD−/− transgenic mouse is displayed along with its appropriate 2C transgenic FADD+ littermate control. Thymocytes were stained by using antibodies to the CD8 and CD4. The percentage for each quadrant is displayed. Each plot represents at least 20,000 events.