Genome context and arrangement of sialic acid catabolism (SAC) and transporter (SAT) gene clusters among Vibrio species. Open reading frames (ORFs) are indicated as arrows, the direction of which shows the direction of transcription. Numbers underneath ORFs represent locus tags. ORFs of similar shading represent homologous genes among the different species examined. The following annotated ORFs are shown: rpiR, transcriptional regulator; nanA, N-acetylneuraminic acid aldolase/lyase; siaPQM, TRAP transporter; nanE, N-acetylmannosamine-6-P epimerase; nanK, N-acetylmannosamine kinase; nagA, N-acetylglucosamine-6-phosphate deacetylase; ABC, ATP-binding cassette transporter; SSS, sodium solute symporter transporter.