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. 2012 May;56(5):2643–2651. doi: 10.1128/AAC.06003-11

Table 4.

Log kill values of different efflux pump KO mutants in the presence and absence of efflux inhibitors

Strain Log kill value (log10 CFU/ml)a
Pyrrole AZI-533 AZI-533 + PAβN Pyrazolone AZI-219 AZI-219 + verapamil
WT Mtuc 0.6 1.7 0 1.4
KO1 1 1.3 0 0.9
KO5 1.9 1.6 3.5 >3.5b
KO6 0.8 1.2 0 1.8
KO7 2.1 2.4 0.6 3.1
a

Log kill values for WT M. tuberculosis and the different efflux pump KO mutants at the highest concentration of the compounds tested.

b

Below the LOQ (limit of quantification).

c

M. tuberculosis.