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Comparative ELF exposures of tedizolid, linezolid, and vancomycin in human and mouse pneumonia models
| Compound | Human ELF AUC0-24 | Mouse ELF AUC0-24 | Mouse regimen |
|---|---|---|---|
| Tedizolid | 109 | 111 | 20 mg/kg q24h |
| LZD | 960 | 910 | 120 mg/kg q12h |
| VAN | 92 | 104 | 25 mg/kg q12h |
