Table 1.
Antibiotic | No. of mice dead after receiving a dose (mg/kg)a of: |
ED50 (mg/kg) | |||||||
---|---|---|---|---|---|---|---|---|---|
0.1 | 1 | 10 | 20 | 40 | 60 | 80 | 100 | ||
Ertapenem | 6 | 6 | 6 | 6 | 5 | 6 | 4 | 3 | 100 |
Imipenem-cilastatin | 6 | 6 | 6 | 6 | 5 | 5 | 5 | 4 | >100 |
Ceftazidime | 6 | 5 | 5 | 1 | 1 | 0 | 1 | 0 | 24 |
Cefotaxime | 6 | 6 | 6 | 6 | 5 | 5 | 6 | 5 | >100 |
Piperacillin-tazobactam | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | >100 |
There were six mice per dose group.