. 2012 May;56(5):2553–2558. doi: 10.1128/AAC.06098-11

Table 1.

MIC, mean FIC, and interaction between FLC and AMB against 14 C. gattii strains

C. gattii strain or parameter^a	MIC (μg/ml)^b			Mean FIC (μg/ml)	Interaction
C. gattii strain or parameter^a	FLC (50%)	FLC (80%)	AMB	Mean FIC (μg/ml)	Interaction
ATCC 24065	2.0	4.0	0.06	1.19	Ind^c
ATCC 32608	8.0	16.0	0.06	1.45	Ind
L135/03 (C)	8.0	16.0	0.06	1.90	Ind
L28/02 (C)	16.0	32.0	0.06	2.18	Ind
23/10993 (C)	8.0	16.0	0.125	1.71	Ind
196L/03 (C)	16.0	32.0	0.06	2.52	Ind
1913 ER (C)	8.0	16.0	0.125	1.42	Ind
547/OTTI/94-PI-10 (E)	32.0	32.0	0.06	1.93	Ind
L27/01 (C)	32.0	32.0	0.06	2.06	Ind
LMM 818 (C)	16.0	32.0	0.125	1.49	Ind
29/10893 (C)	8.0	8.0	0.125	1.07	Ind
L24/01 (C)	8.0	16.0	0.06	2.66	Ind
ICB 133 (E)	8.0	16.0	0.125	0.77	Ind
ICB 181 (E)	8.0	16.0	0.06	1.45	Ind
MIC₅₀	8.0	16.0	0.06
MIC₉₀	32.0	32.0	0.125
MIC range	2.0–32.0	4.0–32.0	0.06–0.125
Geometric mean	10.25	18.22	0.079	1.61	Ind

C, clinical strain; E, environmental strain.

The MIC is given except as noted otherwise in column 1. MIC (50%), MIC endpoint considering 50% of growth inhibition (6); MIC (80%), MIC endpoint considering 80% of growth inhibition (19). FLC, fluconazole.

Ind, indifferent.