Table 1.
Participant characteristics by subgroupa
| Parameter | Value for group |
|||
|---|---|---|---|---|
| TB (n = 50) | DM-TB (n = 26) | HIV-TB (n = 29) | All (n = 105) | |
| % male patients | 48.0 | 65.4 | 90.0*** | 63.8 |
| Mean age (yr) (range) | 31.1 (18–65) | 51.3 (29–79)*** | 34.1 (24–48) | 36.9 (18–79) |
| No. of patients with microbiologically confirmed TB (%) | 38 (76.0) | 22 (84.6) | 17 (58.6) | 77 (73.3) |
| Mean BMI (kg/m2) (range) | 23.3 (18.4–29.6) | 27.5*** (21.9–36.3) | 22.8 (15.8–34.8) | 24.2 (15.8–36.3) |
| No. of patients with diarrhea <15 days (%) | 1 (2.0) | 3 (11.5) | 2 (6.9) | 6 (5.7) |
| No. of patients with chronic diarrhea (%) | 0 (0) | 0 (0) | 2 (6.9) | 2 (1.9) |
| No. of patients with intestinal surgery (%) | 4 (8.0) | 4 (15.4) | 2 (6.9) | 10 (9.5) |
| Mean blood glucose level (mg/dl) (range)b | 92.7 (40–159) | 178.8 (85–441)*** | 92.7 (61–123) | 114.2 (40–441) |
| No. of patients with pathogenic parasites (%)c,d | 4 (8.0) | 1 (3.9) | 4 (14.8) | 9 (8.7) |
| No. of patients with nonpathogenic parasites (%)c | 16 (32.0) | 12 (46.2) | 7 (25.9) | 35 (34.0) |
| No. of patients with intensive-phase treatment (%) | 31 (62.0) | 13 (50.0) | 17 (58.6) | 61 (58.1) |
| Median dose of rifampin received (mg/kg) (range) | 10.1 (7.4–12.6) | 8.8 (5.7–10.9)*** | 10.3 (6.7–15.8) | 9.8 (5.7–15.8) |
Proportions are expressed as cases/total number of patients (percent). Numerical values are expressed as means (ranges). All the tests compared the DM-TB or HIV-TB group to the TB (non-HIV, non-DM) group. Continuous variables were analyzed by using an independent t test, and categorical variables were analyzed with a Pearson χ2 test. BMI, body mass index. ***, P < 0.001, compared with the TB group without a comorbidity.
Results were not available for one TB patient (no comorbidity), one TB-DM patient, and two TB-HIV patients.
Results were not available for 2 HIV patients.
Two HIV patients had asymptomatic giardiasis, 1 patient had Cyclospora cayetanensis, 1 patient had Cryptosporidium parvum, and 1 diabetic patient also had giardiasis; in the TB group, all 4 patients had giardiasis.