Table 3.
Variable | Proportional difference | CI | P valued |
---|---|---|---|
Tmax (6 h) | 0.71b | 0.55–0.93 | 0.012 |
Sex (female) | 1.91c | 1.42–2.56 | <0.001 |
Rifampin dose received | 1.05 | 0.96–1.14 | 0.299 |
Comorbidity | |||
HIV | 0.98 | 0.71–1–37 | 0.926 |
DM | 0.99 | 0.71–1.37 | 0.931 |
The model was considered based on the natural logarithm of the Cmax values. The proportional difference was calculated as the exponential of the coefficient obtained for each variable in the multivariate model.
For interpretations of the proportional difference, Cmax levels in slow absorbers were 29% lower than Cmax levels in fast absorbers.
For interpretations of the proportional difference, Cmax levels in women were 91% higher than those in men.
Boldface indicates significant difference.