Table 1.
Genotype | No. (%) of Pyr-susceptible isolates | No. (%) of Pyr-resistant isolates | Crude OR (95% CI)a | P valueb | Adjusted OR (95% CI) | P valuec |
---|---|---|---|---|---|---|
pfmdr2 | ||||||
F423 | 37 (26.4) | 22 (15.7) | 1 (reference) | 1 (reference) | ||
Y423 | 34 (24.3) | 47 (33.6) | 2.31 (1.11–4.91) | 0.017 | 2.12 (1.02–4.59) | 0.0489 |
pfdhfr | ||||||
Wild type | 28 (20) | 1 (0.7) | 1 (reference) | 1 (reference) | ||
Mutant type | 43 (30.7) | 68 (48.6) | 43.36 (6.67–1,819.1) | <0.0001 | 42.34 (5.52–324.61) | 0.0003 |
OR, odds ratio; CI, 95% confidence interval.
Fisher's exact test.
Multivariate logistic regression model.