Fig 2.

Distribution of initial voriconazole troughs by the age of the patient at the time of the transplant. There was a direct correlation between the age of the patient and initial voriconazole trough (P = 0.005 by Spearman rank correlation). The median age of patients with initial troughs of ≤1 μg/ml was 52 years (IQR, 42 to 64 years) compared to 63 years (IQR, 55 to 68 years) for patients with initial troughs of >1 μg/ml (P = 0.002). The median age of patients with initial troughs of >4 μg/ml was 66 years (IQR, 60 to 71 years) compared to 60 years (IQR, 50 to 67 years) for patients with initial troughs of ≤4 μg/ml (P = 0.02).