. 2012 May;56(5):2241–2245. doi: 10.1128/AAC.05640-11

Table 2.

Steady-state kinetic constants of TMB-1, DIM-1, and GIM-1

Compound	Steady-state kinetic constants of^c:
	TMB-1			DIM-1^a			GIM-1^b
	k_cat (s⁻¹)	K_m (μM)	k_cat/K_m (s⁻¹/μM)	k_cat (s⁻¹)	K_m (μM)	k_cat/K_m (s⁻¹/μM)	k_cat (s⁻¹)	K_m (μM)	k_cat/K_m (s⁻¹/μM)
Ampicillin	3.3	27	0.122	20	110	0.182	3.3	20	0.165
Piperacillin	3.3	72	0.046	NR	NR	NR	6.9	69	0.1
Cefoxitin	0.3	69	0.004	8	20	0.4	8.3	206	0.04
Cefuroxime	0.1	9	0.011	NR	NR	NR	5.9	7	0.843
Ceftazidime	0.07	31	0.002	3	50	0.06	18	31	0.58
Ertapenem	0.4	31	0.013	NR	NR	NR	NR	NR	NR
Imipenem	1.7	200	0.009	35	80	0.438	27	287	0.094
Meropenem	1.4	75	0.019	50	10	5	2.7	25	0.108
Aztreonam	<0.01	ND	ND	<0.01	ND	ND	ND	ND	ND

Data are from Poirel et al. (12).

Data are from Castanheira et al. (3).

NR, not reported. ND, not detected.