Figure 2.

Apoptosis and UPR-associated proteins induced by KW-2478 and bortezomib (BTZ) in MM cell lines. (a) OPM-2/GFP cells were treated with KW-2478, (BTZ) alone, or their combinations for 3 h, and further incubated in drug-free medium for 21 h, followed by western blotting. (b) NCI-H929 cells were examined as described in (a).