Table 2.
Base-case transtubular transport parameters
| CD | ATL | AVR | DVR | |
|---|---|---|---|---|
| Transport parameters | ||||
| Pf, μm/s | 450 (4) | 0 | 5,260 (27) | 1200 |
| PNa, 10−5 cm/s | 1 | 80 | 100 | 74 (29) |
| PCl, 10−5 cm/s | 1 | 80 | 100 | 74 (29) |
| Purea, 10−5 cm/s | 2 | 1 | 100 | 74 (29) |
| Luminal compositions | ||||
| CNaCl, mM | 140 | 317 | 322* | 337 |
| Curea, mM | 500 | 133 | 178* | 120 |
| Osmolality, mosmol/kg H2O | 742 | 712 | 765* | 736 |
| Pressures | ||||
| Δπ, mmHg | — | — | 10.3 | — |
| p, mmHg | 5.5 | — | 8.0 | 9.2 |
Pf, PNa, PCl, Purea, permeability of water, Na, Cl, and urea; CNaCl and Curea concentration of NaCl and urea; p, hydrostatic pressure; ΔΠ, oncotic pressure; DVR, descending vasa recta.
*
Upstream concentration values.