Table 2.
Stage | No. of Studies | No. of Patients | N1a | N2b | Overallc | |||
---|---|---|---|---|---|---|---|---|
NPV | 95% CI | NPV | 95% CI | NPV | 95% CI | |||
I | 7 | 624 | 0.92 | 0.89, 0.96 | 0.95 | 0.93, 0.97 | 0.87 | 0.80, 0.93 |
IA | 4 | 360 | 0.92 | 0.89, 0.94 | 0.95 | 0.93, 0.97 | 0.86 | 0.82, 0.89 |
IB | 1 | 61 | 0.75 | 0.62, 0.85 | 0.85 | 0.73, 0.92 | 0.61 | 0.47, 0.73 |
Abbreviations: CI = confidence interval; NPV = negative predictive value.
Hilar nodal metastasis alone.
Mediastinal nodal metastasis with or without N1 disease.
Positive nodal disease at N1 or N2.