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. 2012 May 7;7(5):e36460. doi: 10.1371/journal.pone.0036460

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Parrott et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A–C) The percentage of pHH3-positive GSCs for each indicated genotype. (A) The expression of s-spi in germ cells rescues the hyper-proliferation of GSCs in spi^77-20 testes. (B) GSCs in stet¹/stet³ testes showed an increased M-phase index compared to w¹¹¹⁸ testes. (C) RNAi-mediated knock-down of EGFR in the soma causes a higher GSC M-phase index, ***p-value≤0.0001.