Figure 1. Odds ratios for haplotypes carrying any combination of A*02, C*05 and B*12.

Odds ratios for haplotypes containing one or two of the allele groups of the protective class I haplotype compared to the full protective class I haplotype disregarding the DRB1 locus. Chromosomes carrying both A*02 and B*12 was the only combination within this setting that had the same risk as the protective haplotype, the risk of MS was significantly higher for all other combinations.“+” = Chromosomes carrying the allele group specified to the left, “H−” = chromosomes carrying other allele group than the one specified to the left (i.e. not the complete protective haplotype). OR = odds ratio with 95% confidence interval, nominal p-value and Bonferroni corrected p-values derived from chi square test with full protective haplotype as reference.