Table 1. Risks carried by each of the nominally significant allele groups from the final logistic regression analyses.
Allele group | p-value (nominal) | p-value (FDR) | OR (95% C.I.) | Frequency Cases (%) | Frequency Controls (%) |
DRB1*15 (dose) | 2.51×10−63 | 2.26×10−62 | 3.03 (2.67–3.46) | 35.4 | 15.3 |
A*02 | 5.42×10−08 | 2.44×10−07 | 0.67 (0.58–0.77) | 27.7 | 34.6 |
B*14 | 6.96×10−05 | 0.00013 | 2.05 (1.45–2.94) | 2.7 | 1.8 |
DRB1*07 | 0.0016 | 0.0020 | 0.70 (0.56–0.87) | 5.0 | 8.5 |
B*12 | 0.0025 | 0.0028 | 0.76 (0.63–0.91) | 8.8 | 13.1 |
DRB1*01 | 0.034 | 0.034 | 0.82 (0.68–0.98) | 7.7 | 11.9 |
FDR = False discovery rate, performed in R, based on the paper [37].