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. 2012 May 7;7(5):e36779. doi: 10.1371/journal.pone.0036779

Table 4. Frequencies of estimated haplotypes, odds ratios and p-values from logistic regression with the 20 most common haplotypes.

Haplotype
No. HLA-A HLA-C HLA-B HLA-DRB1 Cases Controls Frequency Cases (%) Frequency Controls (%) Frequency Total (%) Nominal p-value FDR corrected p-value Odds Ratio (95% CI)
1. 1 7 8 3 207 240 7.0 8.6 7.7 0.022 0.033 0.78 (0.63–0.96)
2. 3 7 7 15 226 118 7.6 4.2 6.0 2.97×10−07 2.28×10−06 1.90 (1.49–2.44)
3. 2 7 7 15 179 59 6.0 2.1 4.1 1.18×10−12 2.72×10−11 3.14 (2.31–4.34)
4. 2 3 15 4 53 86 1.8 3.1 2.4 0.0066 0.015 0.60 (0.42–0.87)
5. 3 4 35 1 42 72 1.4 2.6 2.0 0.0030 0.0087 0.54 (0.36–0.81)
6. 2 5 12 4 25 81 0.8 2.9 1.8 1.39×10−07 1.60×10−06 0.28 (0.17–0.45)
7. 9 7 7 15 78 23 2.6 0.8 1.7 1.45×10−06 8.33×10−06 3.30 (2.06–5.47)
8. 2 3 40 6 38 56 1.3 2.0 1.6 0.068 0.097 0.67 (0.43–1.03)
9. 10 12 18 15 44 22 1.5 0.8 1.1 0.011 0.021 2.00 (1.19–3.48)
10. 3 3 15 4 33 15 1.1 0.5 0.8 0.0078 0.016 2.35 (1.27–4.52)
11. 1 6 37 15 37 10 1.2 0.4 0.8 0.00021 0.00095 3.87 (1.97–8.35)
12. 2 5 12 15 24 23 0.8 0.8 0.8 0.80 0.82 0.92 (0.51–1.69)
13. 1 7 7 15 30 15 1.0 0.5 0.8 0.020 0.032 2.15 (1.15–4.19)
14. 11 4 35 1 22 21 0.7 0.8 0.7 0.59 0.68 1.19 (0.63–2.23)
15. 19 16 12 7 21 22 0.7 0.8 0.7 0.82 0.82 0.93 (0.49–1.74)
16. 19 3 40 4 12 31 0.4 1.1 0.7 0.0063 0.015 0.38 (0.18–0.74)
17. 2 7 8 3 16 26 0.5 0.9 0.7 0.076 0.10 0.56 (0.29–1.05)
18. 2 3 40 4 17 24 0.6 0.9 0.7 0.20 0.26 0.65 (0.34–1.25)
19. 2 3 15 6 16 24 0.5 0.9 0.7 0.23 0.28 0.67 (0.34–1.27)
20. 3 7 7 4 16 18 0.5 0.6 0.6 0.66 0.72 0.85 (0.42–1.71)