Table 2.
Urine metabolite | GM prepregnancy median (25th, 75th percentile)a | GM pregnancy median (25th, 75th percentile)a | Correlationb | Percent difference between pregnancy and prepregnancy concentration (95% CI)c | ||||
---|---|---|---|---|---|---|---|---|
ΣDEHP metabolitesd (μmol/L) | 0.33 (0.20, 0.56) | 0.36 (0.18, 0.69) | 0.33 | 9 (–8, 29) | ||||
ΣDEHP oxidative metabolitese (μmol/L) | 0.30 (0.18, 0.52) | 0.31 (0.17, 0.66) | 0.34 | 8 (–9, 28) | ||||
MEHP (μg/L) | 5.0 (2.8, 7.7) | 5.9 (3.2, 13) | 0.32 | 29 (8, 55) | ||||
MBP (μg/L) | 14 (9.0, 22) | 16 (11, 24) | 0.62 | 25 (11, 41) | ||||
MiBP (μg/L) | 5.4 (3.2, 8.9) | 5.9 (4.0, 9.0) | 0.55 | 9 (–4, 23) | ||||
MBzP (μg/L)f | 3.2 (1.8, 5.2) | 3.7 (2.0, 6.8) | 0.54 | 22 (6, 40) | ||||
MEP (μg/L)f | 61 (37, 145) | 55 (24, 116) | 0.62 | –19 (–30, –6) | ||||
BPA (μg/L) | 1.5 (1.1, 2.1) | 1.5 (1.1, 2.3) | 0.39 | 6 (–4, 17) | ||||
aMedian and percentiles of the within-woman GM of urinary phthalate metabolite or BPA concentrations in two or more samples obtained before pregnancy and during pregnancy. bPearson correlation coefficients between the GM of prepregnancy and pregnancy urinary phthalate metabolite or BPA concentrations (log10 transformed). cPercent difference in pregnancy versus prepregnancy urinary phthalate metabolite or BPA concentration; estimated with a linear mixed model with an indicator variable for pregnancy or prepregnancy (referent). dΣDEHP metabolites: mono(2-ethyl-5-carboxypentyl) phthalate (MECPP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP), and mono(2-ethylhexyl) phthalate (MEHP). eΣDEHP oxidative metabolites: mono(2-ethyl-5-carboxypentyl) phthalate (MECPP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), and mono(2-ethyl-5-oxohexyl) phthalate (MEOHP). fA correction factor of 0.66 and 0.72 was applied to the MEP and MBzP concentrations, respectively. |